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The standard toolkit includes: filing secondary patents on drug delivery devices (autoinjectors, prefilled syringes), formulation patents (concentration, excipient composition), method-of-use patents (new indications, dosing regimens), and process patents (crystalline form, manufacturing method)

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What we tell patients: Keep training, but dont try to PR every session Reduce intensity on the affected area for the first 2 to 3 weeks Add mobility work, not subtract it Listen to pain signals

The metabolites associated with glycolysis, tricarboxylic acid cycle (TCA cycle), and urea cycle, as well as amino acids and coenzymes did not exhibit clear changes indicating activated metabolic pathways (Fig