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Table of Contents Week 1: Metabolic Foundation Setting Week 2: Energy System Activation Weeks 3-4: Metabolic Optimization Weeks 5-8: Early Body Composition Changes Weeks 9-12: Significant Metabolic Changes Weeks 13-16: Metabolic Reset Completion Factors That Affect the Timeline By Use Case: Specialized Timelines When to Adjust the Protocol Realistic Expectations by Timeline Related Reading References What to Expect: Minimal visible changes Possible mild energy fluctuations Some users report improved sleep quality What's Happening Internally: Research shows NNMT inhibition begins immediately, with cellular NAD+ levels starting to rise within days

What we dont have: a named individual prescriber for CMS NPPES lookup, or the pharmacy class (503A vs 503B) handling their compounding

This conservative protocol prioritizes long-term safety while still achieving meaningful telomerase activation

However, body composition changes remain minimal in the early phase