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Acknowledgements This work was funded by grants RTI2018-094052-B-100 funded by MICIU/AEI/10.13039/501100011033/ and by ERDF A way of making Europe and PID-2021-122766OB-100 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU, P2022/BMD-7227 (Comunidad de Madrid, Spain) and CIBERDdem (ISCIII) to A.M.V

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A 2025 meta-analysis highlighted a 30% higher risk of all-cause mortality in middle-aged and older individuals with low lean mass compared to those with normal lean mass