flu like symptoms semaglutide Side Effects: A Week-by-Week Guide & When to Call Your Provider Ozempic Side Effects: Risks of

What the evidence shows The approval rests primarily on OASIS 4, a phase 3 randomised, double-blind, placebo-controlled trial of 307 adults with overweight or obesity and without diabetes, randomised 2:1 to oral semaglutide 25 mg or placebo for 64 weeks alongside lifestyle support (Wharton et al., 2025)

Like other GLP-1 receptor agonists , semaglutide must be stored properly to remain safe and effective

GLP-1 receptor agonists such as semaglutide, liraglutide, and tirzepatide are widely prescribed in the UK for type 2 diabetes and weight management, but their effects on gastric emptying and appetite have important implications for post-operative care

8.2 Constipation and Abdominal Discomfort Altered gastrointestinal motility may lead to constipation or bloating