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55 To recapitulate, GIP appears to have a dose-related, binary relationship with adipose tissue inflammation

Your healthcare provider will have to inform Cigna that you have performed behavioral modifications (e.g., increasing exercise) and a reduced-calorie diet for at least three months, and have either: A BMI of 30 or higher, or A BMI of 27 or higher, plus a weight-related comorbidity approved by Cigna, such as hypertension, Type 2 diabetes, dyslipidemia (high cholesterol), obstructive sleep apnea, or cardiovascular disease Wegovy is also FDA approved for cardiovascular risk reduction

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Eli Lilly: Tirzepatide/Mounjaro Lily initially developed Tirzepatide as a dual agonist, with a half-life of around 5 days, for the treatment of T2DM