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Observational studies have tracked the effects of caloric restriction on lean, healthy individuals, and demonstrated that moderate restriction (2230% decreases in caloric intake from normal levels) improves heart function and reduces markers of inflammation (C-reactive protein, tumor necrosis factor [TNF]), risk factors for cardiovascular disease (LDL cholesterol, triglycerides, blood pressure), and diabetes risk factors (fasting blood glucose, insulin levels)

To view or add a comment, sign in #GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety

To counteract this, researchers have turned to Growth Hormone Secretagogues (GHS)

Szabo G, Mitchell M, McClain CJ, Dasarathy S, Barton B, McCullough AJ, et al