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This antioxidant action is critical in neurodegenerative conditions such as AD and PD, where oxidative stress accelerates neuronal damage [121]

Overall, given the limited number of studies assessing age-related changes in brain GSH levels, we recommend additional investigations (a) for all age groups, but in particular, the understudied middle-aged group, and (b) MRS at UHF (i.e., 7T)

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In pancreatic ductal adenocarcinoma FOXO3 is able to induce stem cell properties, associated with poor prognosis and possibly metastasis [118, 119]