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Inflammation : High levels of inflammation in the brain are linked to increased blood-brain barrier (BBB) permeability [5] Stress : Acute stress activates brain mast cells that secrete proinflammatory cytokines [6] Bacterial infections : Bacteria in the brain increase MMP activity, which may induce the breakdown of the BBB [7] Toxins : LPS induces inflammation [8] Mold toxins : Mold toxins and mold components trigger inflammation and increase oxidative damage in the brain [9] High-fat , high-calorie diet : High-fat diets may increase oxidative damage, hypoxia, and inflammation in the brain [10] Leaky gut : Changes in the gut have been associated with BBB permeability [11, 12] Liver damage : In acute liver failure, the damaged liver releases MMP9 into the bloodstream, which may damage tight junctions [13] Diabetes or high blood sugar : Changes in glucose levels cause oxidative stress and inflammation [14] Disrupted sleep -wake cycle : Chronic sleep disturbance decreases glucose transport across the BBB and increases inflammation [15] Anything that triggers oxidative stress in glial cells and pericytes: Oxidative stress damages the BBB and causes structural and integrity problems [16, 17] Hypoxia : Hypoxia is a condition where there is not enough oxygen available

Balikian, MD, FACS Double Board-Certified Facial Plastic Surgeon Balikian Plastic Surgery 951-719-2950 25220 Hancock Ave STE 115, Murrieta, CA 92562 Balikian Facial Plastic Surgery 858-230-8938 1431 Camino Del Mar, Del Mar, CA 92014 This site uses cookies

More bacteriostatic water lowers the concentration and raises the units drawn for the same dose

Integrative medicine, as practiced by Dr