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Melatonin also activates the mitochondrial autophagy pathway: upregulating expression of PINK1/Parkin and the autophagy marker LC3 results in the degradation of damaged mitochondria (decreased P62 expression) and the maintenance of mitochondrial health [121]

Consider Telehealth Options If your primary care doctor is unable to prescribe these medications, or if you want a provider who specializes specifically in metabolic health, telehealth platforms are a viable alternative

This ongoing supervision is what separates a safe, effective outcome from a guesswork approach

since the antioxidant status of an individual varies widely, it is plausible that this can significantly influence the effect of exogenous supplementation