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Senescence-associated -galactosidase (SA--gal) activity was measured in both cells and frozen tissues using a commercial kit, providing a visual and quantitative indicator of senescent cells
The article says DPP-4 inhibitors such as sitagliptin, saxagliptin and linagliptin block the enzyme that breaks down the incretin hormones GLP-1 and GIP, which raises native GLP-1 levels in the bloodstream
Furthermore, among those already with a SUD, GLP-1s appeared to lower hospitalizations, overdoses, and death, GLP-1 receptor agonists are not replacements for current medication treatments for AUDbut may soon become important additions
PloS One 8, e73259
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