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These symptoms, especially whenever combined with hoarseness or trouble swallowing, could indicate serious conditions requiring swift intervention

Orforglipron helped patients lose 12.4 per cent of their weight on average after 72 weeks, less than the 14.9 per cent weight loss seen in a previous trial of Novos Wegovy over 68 weeks and below what analysts were expecting

The landmark SURMOUNT-1 clinical trial , for example, found that participants with obesity or who were overweight lost an average of 15% to 22.5% of their body weight over 72 weeks