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Cloudiness, particles, discoloration, or changes in appearance signal potential degradation and indicate the vial should not be used, even if within the recommended timeline

Although the association between the deficiency of G6PD and the non-immune hemolytic and the non-spherocytic anemia 22 is clearly defined, also it is evident its correlation with the hemolysis due to medicines, food and to other events such as infection processes, situation outlined by Vulliamy et al

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The seven subjects who did not complete the study failed to attend follow-up testing due to time constraints, work, or family responsibilities