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As a glucose sensor, GLUT2 carries glucose into cells in the physiological state and works with glucokinase (GCK) to quickly adjust the amounts of glucose on either side of the cell membrane to achieve equilibrium and match the concentration of glucose in the environment
J Physiol 581:431444 Stephens FB, Evans CE, Constantin-Teodosiu D, Greenhaff PL (2007b) Carbohydrate ingestion augments l-carnitine retention in humans
Eric Topol (22:22): That's a very important point you're making because I think we conceive of these drugs as anti-inflammatory agents from these more diverse actions that we've just been reviewing
The key issue is that the hepatotoxicity of these drugs occurs at therapeutic doses in a limited number of patients, placing them somewhere between intrinsic and idiosyncratic hepatotoxins
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