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2 Levodopa remains the mainstay for the treatment of PD and is referred to as the gold standard

However, excessive copper exposure can worsen the condition, and therapeutic efficacy may depend on the presence of A deposition, as copper shows little effect in models without amyloid deposits

This is in agreement with recent metabolomic analyses showing that breastfeeding is the most dominant factor associated with gut metabolite levels, impacting metabolite concentrations up to 30 months of age (Aatsinki et al., 2025)