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In summary, modulating the surface charge of nanoparticles can improve their ability to deliver drugs into the CNS via the endogenous transport mechanism of the BBB

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Concentrations of GSH were significantly higher than those of GSSG, with values of up to 40 mg/g for GSH compared with 5.1 mg/g for GSSG (Figure 2)

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Not drinking enough water can worsen the side effects, too

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