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10.1155/2011/489470 139 WuZ.YamaguchiY

Tracking GABAergic axons dynamics in vivo has been possible by implanting cranial widows in mice expressing a fluorescent protein in a subpopulation of inhibitory neurons and visualizing inhibitory presynaptic structures using confocal microscopy in superficial cortical layers (Keck et al., The postsynaptic side plasticity Although tracking presynaptic structures identifies changes in putative inhibitory synaptic contacts the fluorescent tagging of the scaffolding protein gephyrin allows dynamic visualization of the postsynaptic component of GABAergic synapses (Figure 3)