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Additionally, Tg PLP treatment triggered immune responses as evidenced by increased expression of antigen-presenting cell markers (MHC class I and II, B7.1, and B7.2) in bone marrow-derived macrophage and increased IL-12 and IFN- expression in mice
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Cardiovascular risk markers (non-HDL cholesterol, triglycerides, hsCRP, systolic blood pressure -14.0 mmHg at the highest dose) all improved significantly
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