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DES(1-3) IGF-1 signals through the same IGF1R PI3K/AKT and MAPK/ERK axes as IGF-1 LR3 but, because it lacks the N-terminal extension that confers extended half-life in LR3, its circulating stability is more comparable to native IGF-1

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A human putative lymphocyte G0/G1 switch gene containing a CpG-Rich island encodes a small basic protein with the potential to be phosphorylated