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Quantified Benefits: 66% Reduction in Shedding: Post-surgical graft shedding (shock loss) was reduced from a standard 30% down to only 10%

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Oxidative phosphorylation modulators By competitively inhibiting long-chain 3-keto-CoA sulfatase, trimetazidine shifts myocardial metabolism from fatty acid -oxidation to glucose oxidation, thereby optimizing energy production during episodes of ischemia