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All participants signed a written informed consent form (supplementary materials 710), and the protocol was reviewed and approved by the Institutional Ethics Committee of the First Affiliated Hospital of Hebei North University (approval no

Pyramid-shaped columnar epithelial cells and paneth cells, located at the base of small intestinal crypts (95), are crucial for innate immunity and host defense against fungi, bacteria, and certain viruses

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The p53 protein reduces the transcriptional expression of phosphoglycerate mutase (PGM)