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Other Interactions With Sertraline (Zoloft) dronedarone (Multaq), a medication for irregular heartbeats Monoamine oxidase inhibitors (MAOIs), including isocarboxazid (Marplan), phenelzine (Nardil), selegiline, and tranylcypromine (Parnate) linezolid (Zyvox), an antibiotic that carries out similar activity to MAOIs Certain antipsychotic medications, including pimozide and thioridazine An injected medication called methylene blue (ProvayBlue) Amphetamine Anticoagulants or blood thinners Anti-seizure medications Aspirin and other anti-inflammatory drugs Diuretics, or water pills Fentanyl, an opioid pain-relief medication Medications for anxiety Medications for irregular heartbeat Migraine medications Sedatives and sleep-inducing medications Other antidepressants If you take any of the above, a doctor may need to adjust your dose or monitor you for side effects