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3.2 The mechanisms of GLP-1/GIP or GCG receptor dual agonists in MASLD 3.2.1 Metabolic regulatory effects Dual agonists targeting GLP-1 and GIP receptors have emerged as promising agents for metabolic regulation in MASLD

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[5] Notably, normal feedback mechanisms remain intact: elevated IGF-1 and GH can signal the hypothalamus and pituitary to modulate further hormone release, which may reduce the risk of extreme hormone levels