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To achieve this goal, we designed the virtual screening scheme depicted in Supplementary Figures S2

However, to clearly understand the mechanisms and level of toxicity of sALS astrocytes, it remains to be investigated if sALS and fALS astrocytes are equally detrimental to motor neurons upon activation [in response to an ALS environment or to lipopolysaccharide (LPS)] and their secretion pattern in such a context

Bariatric Surgery Consultation Available on the NHS for qualifying patients, often through Tier 4 services

These might include different muscle relaxants, nerve pain medications, physical therapy, or lifestyle changes