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In fact, oxidative stress plays a key role in the onset and progression of the complications of diabetes

Semaglutide the active ingredient in Ozempic and Wegovy is a GLP-1 receptor agonist that restores appetite and satiety signaling blunted by metabolic dysfunction

These findings underscore the urgent need for targeted antioxidant therapies capable of quenching this systemic ROS burden and restoring metabolic homeostasis

The relationship between adipose tissue (AT) and glucose metabolism in PWS remains largely unknown, although several studies have observed indices of lower IR compared to controls (166, 183, 184)