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Data from the EFFISAYIL program show spesolimab provides: Sustained reduction in flare frequency over 3 years ~75% of patients remaining flare-free Stable safety profile with no new signals Given the severity and unpredictability of GPP, these findings reinforce the value of targeted IL-36 inhibition for durable disease suppression

But there was something really special about learning about each other in those moments that felt like, Oh, hes a contrarian and thats fun

The mechanism involves reduced gallbladder contraction and increased bile saturation during calorie restriction

If left untreated, ileus can cause parts of the intestine to die, leading to major problems or death for patients