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To identify the full extent of the differential signaling responses to ligand stimulation between WT-IR and L973F-IR, we also compared the fold changes of each phosphosite between basal and stimulated conditions in these 2 cell types for both up- and downregulated phosphorylation in a volcano plot (Figure 3C)

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Galanin Galanin is a widely distributed peptide that is found in the CNS and PNS, as well as in non-neural tissues (160)