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Byetta is indicated as a addition to diet and exercise in adults with type 2 diabetes and is dosed twice daily via subcutaneous injection

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ERK5 shares high identity with ERK1/2 but has a unique and extended C-terminal tail (410816 aa), which contains a nuclear localization signal sequence, a myocyte enhancer factor 2 (MEF-2)-interacting domain, and a transcriptional activation domain [29]

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