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The STEP 1 trial used 2.4 mg as the target maintenance dose and achieved average weight loss of 14.9% of body weight over 68 weeks

In the US, these medications carry a black-box warningthe strongest safety cautionbecause they have been linked to thyroid cancers in rodents, though human evidence remains inconclusive

And have a backup plan in case you need to transition to another provider

NHS and Manufacturer Recommendations: Use a barrier method (like condoms) for at least 4 weeks after starting Mounjaro Also apply the 4-week barrier rule after each dose increase Consider switching to non-oral forms of contraception (e.g., patch, IUD, implant) 2