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Det er desuden vrd at bemrke, at en anden klasse af antidiabetika med signifikant effekt p risikoen for kardiovaskulr sydom [30], nemlig SGLT-2-hmmere, medierer deres effekt gennem helt andre virkningsmekanismer, hvorfor en additiv kardiovaskulr effekt ved kombineret behandling med GLP-1-receptoragonist og SGLT-2-hmmer ikke kan udelukkes