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However, these changes reflect metabolic improvements associated with weight loss rather than any direct effect on the autoimmune process or thyroid gland itself

The information in Item 7.01 of this Current Report on Form 8-K and in Exhibit 99.1 attached hereto is being furnished and shall not be deemed filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the Exchange Act) or otherwise subject to the liabilities of that section, nor shall they be deemed incorporated by reference into any filing by the Company, under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing

The 71 differential peptides were degradation products from a variety of proteins, including several previously associated with IC/BPS from prior proteomics studies (Table 1) 21,22,23

How is this calculated