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When HFD fed rats were given Zingiberene at the dose of 50 mg/kg body weight it attenuates hyperlipidaemia, hyperglycemia, hyperinsulinemia in both liver and blood further, it reduces the elevated lipogenesis and oxidative stress in liver along with this it regulate activities of carnitine palmitoyl transferase, acetyl-CoA carboxylase, fatty acid synthase, and HMG CoA reductase [149]
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The cystine transporter SLC7A11 critically restores/maintains intracellular GSH
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