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The SELECT trial (NEJM, 2023) showed a 20% reduction in major cardiovascular events in patients taking semaglutide

FDA guidance for RUO and investigational labeling in the IVD context stresses that RUO labeling is tied to laboratory research positioning and should not be used to imply broader product status [17] [18]

The additional carbohydrate, and the requirement to specifically be timed with the carnitine supplement twice daily, is unlikely to align with the caloric needs and nutrient timing that is optimal for each athlete, during each phase of training, over the period of supplementation

The real game-changer has been the impressive results these drugs deliver