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Several mechanisms may potentially contribute to blood pressure effects, including: weight loss (a well-established factor in blood pressure reduction), possible promotion of natriuresis (sodium excretion by the kidneys), and theoretical improvements in endothelial functionthough many of these mechanisms remain hypothetical rather than definitively proven

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Therefore, it is suggested that GLP-1RAs are optimal anti-diabetic medicines for T2D patients with normal BMI, being successful in both reducing glucose levels and maintaining a stable body weight

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