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Moreover, Gln is an essential substrate for the immune system, and prolonged use of Gln metabolic inhibitors might weaken the anti-tumor immune response ( 2 The role of Gln metabolism in tumor Emerging evidence shows that Gln metabolism is involved in tumor progression in two specific ways ( Figure 1 )
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A 2025 review of research papers and patents by Jzwiak and colleagues examined the larger BPC-157 literature, reviewing preclinical data across cellular signaling, tissue biology, pharmacology, and other areas of scientific investigation