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Fink-Jensen et al
In cultured somatotroph models the GHRH receptor (a class-B GPCR) couples to Gs / adenylyl cyclase, raising cAMP and activating PKA / CREB signaling associated with growth-hormone gene expression
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HEK-Blue GLP-1 cells strongly respond to the incretin GLP-1 (7-36) amide, but not to other G protein-coupled receptor (GPCR)-activating peptide hormones, such as GIP (glucose-dependent insulinotropic polypeptide) or glucagon
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