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The current advancement in patient-derived organoids (PDO) generation protocols (91, 92) and the creation of several PDX collections (9396) will enable complex studies in identifying targetable metabolic vulnerabilities in different disease stages

Those mice lost a lot of weight compared to other mice that got bacteria from people who hadn't had the surgery [9]

Several studies undertaken globally show that women with vitamin B12 deficiency in early pregnancy were up to five times more likely to have a child with neural tube defects, such as spina bifida, compared to women with high levels of vitamin B12

The low volume of drug required for intrathecal dosing rarely poses a problem