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L-carnitine supplementation resulted in significant carnitine plasma level increase by week 4

An 8-week trial of supervised weight reduction with low-energy diet showed a mean weight loss of 14.2 kg, and significant improvement was observed in individuals in the intervention group in forced expiratory volume at one second (FEV1), forced vital capacity (FVC), dyspnea, use of rescue medication, and number of exacerbations, compared with controls [42]

At the end of the second cycle of treatment and after 28 months of multimodal treatment, the patient underwent follow-up with physical examination and penile Doppler ultrasound