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Apolipoprotein E4 association with metabolic syndrome depends on body fatness

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Cell 175 , 679694 e622 (2018)

Key Facts: Full Name : Glucose-dependent insulinotropic polypeptide Also Known As : Gastric inhibitory polypeptide (older term, now less favored) Produced By : K-cells in the proximal small intestine Stimulus for Release : Nutrient ingestion, especially glucose and fat Main Actions : Stimulates insulin secretion (only when glucose is elevated) Influences fat metabolism Modulates energy balance and satiety May impact bone turnover and neuroprotection Where Is GIP Produced