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Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, et al

Several large-scale cardiovascular outcome trials (including LEADER, SUSTAIN-6, and REWIND) have shown that certain GLP-1 receptor agonists liraglutide, semaglutide, and dulaglutide reduce the risk of major adverse cardiovascular events such as heart attack, stroke, and cardiovascular death in people with established cardiovascular disease or multiple cardiovascular risk factors

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Contrarily, in all BPC 157-treated rats, from the very beginning, the lesion was markedly smaller (half the size, given the very large lesion in the controls), with less edema, necrosis of muscle fibers, and acute inflammation with foci of abscessation