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In addition, activation of GLP-1Rs has anti-inflammatory effects via stimulation of AMPK, cAMP, endothelial nitric oxide synthase (eNOS), and suppression of chemokine expression (Jin and Liu 2020)

The compound's design as a competitive inhibitor fused with HIV-TAT for cellular uptake represents advanced peptide engineering that enables intracellular delivery and specific protein-protein interaction disruption, providing researchers with tools for studying senescence mechanisms that were previously inaccessible

Diabetol Int 8(2):218227

However, it is still best to follow the dosage instructions on the supplement label or from your health practitioner