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Patients with certain genetic variants may respond more strongly to semaglutide monotherapy, while others benefit from dual-pathway activation using tirzepatide or GLP-Squared combinations

sustained high SC dosing must replicate exposure without compromising the peripherally restricted profile

Further research is needed to fully understand the long-term effects and safety profile of this medication but the results of this study provide a promising foundation for future investigations

Instead, research suggests it works by inhibiting Hepatocyte Growth Factor Activator Inhibitor (HAI-1), an enzyme that normally limits HGF activity