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[48] Die Behandlung mit L-Carnitin reduzierte die Sterberate 5 Tage nach der Randomisierung signifikant, beeinflusste das Risiko einer Herzinsuffizienz oder eines Todes nach 6 Monaten jedoch nicht signifikant

In addition, the high glucose environment also significantly increased ROS and LPO levels, which inhibited GPX4 activity leading to disruption of mitochondrial integrity (95)

[1] Acute kidney injury has been reported, particularly in patients experiencing severe gastrointestinal adverse reactions with volume depletion

These strategies have succeeded for small-molecule drugs and a limited number of short peptide fragments