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NO could be then oxidized to nitrate by myoglobin and hemoglobin in the body [40], and studies have revealed that nitrate can be converted into nitrite in the body, creating a nitrite-nitrate-NO cycle

10.1016/j.archoralbio.2012.02.008 Arch

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however, the differences between the vitamin and placebo groups were not statistically different at any of the measured timepoints (3 months, 6 or 9 months, and 12 months) (103)