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Vitamin B12 is associated with lowering the levels of homocysteine, an amino acid that is associated with cardiovascular disease

As mentioned previously, the widespread and prolonged use of histamine H 2 -receptor blockers and proton pump inhibitors for ulcer disease also may cause impaired breakdown of vitamin B 12 from food, causing malabsorption and eventual depletion of B 12 stores

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Multiple forms of the transcobalamin transport molecule exist the one that is important here is transcobalamin II, as it allows B12 to become biologically available