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Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

Studies show that most people regain a significant portion of the weight if they stop the medication without a very strict, long-term maintenance plan

doi: 10.1016/j.jhep.2021.06.034

Research has shown it stimulates growth hormone release without significantly affecting cortisol or prolactin, making it one of the most selective GH secretagogues available