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What sets GHK-Cu apart in the research literature is scale: naturally occurring levels of the peptide in human plasma decline from roughly 200 ng/mL at age 20 to about 80 ng/mL by age 60, a drop researchers have used as a starting point for studying its potential connection to age-related changes in tissue repair

Yang X, Chen Y, Guo J, Li J, Zhang P, Yang H, Rong K, Zhou T, Fu J, Zhao J (2023) Polydopamine nanoparticles targeting ferroptosis mitigate intervertebral disc degeneration via reactive oxygen species depletion, iron ions chelation, and GPX4 ubiquitination suppression