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The question remains how the type IV secretion system translocates the CagA protein into gastric epithelial cells

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Although these experiments had no effects on tumor viability, the concept was later picked up by Wilhelm Brnings 178 , 179 who combined maximally tolerable doses of insulin treatment with a KD into a de-glycation method (Entzuckerungsmethode) for the treatment of head and neck cancer patients in his clinic

Oligospermia has been reported in patients receiving systemic ketoconazole in investigational studies