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10.1002/da.22051 118 MayerE

Increased energy levels is probably the most common benefit we hear about

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

Therapeutic applications focus on insomnia and difficulty falling or staying asleep, insufficient deep sleep despite adequate sleep duration, sleep disruption from stress or irregular schedules, recovery optimization for athletes or high performers, circadian rhythm disorders from travel or shift work, sleep quality decline associated with aging, and comprehensive wellness protocols recognizing sleep as foundational to metabolic health, cognitive function, immune resilience, and longevity