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By reducing excessive glucagon release, GLP-1 agonists decrease hepatic glucose output and improve overall glycemic control

Inkretine und Wirkmechanismen Die Entdeckung der Inkretinhormone GIP (Glucose-dependent Insulinotropic Polypeptide) in den 1970er-Jahren und GLP-1 (Glucagon-like Peptide 1) in den 1980er-Jahren erffnete neue therapeutische Mglichkeiten

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Popoola and Obembe, 2013)