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As we age, we become more and more aware of our joints

Predrag Sikiric and his research team at the University of Zagreb, Croatia

We now report that shunting of glutamate derived from glutathione can shape excitatory neurotransmission

Maintaining adequate hydration is essential, particularly with topiramate Metabolic monitoring : Regular assessment of kidney function, electrolytes, and acid-base balance is advisable Weight loss monitoring : Whilst often desired, excessive or rapid weight loss should be evaluated Cognitive function : Topamax's cognitive effects may be more problematic if compounded by any metabolic disturbances If you experience severe or persistent side effects, contact your healthcare provider promptly